Endocrine Abstracts

A 25-year lady was referred to GSTT for further management of thyrotoxicosis as she had relocated to London. The patient developed thyrotoxicosis during her pregnancy at the age of 23. During her pregnancy, she had significant weight loss. Her thyroid function test in September 2020 showed TSH 0.04 mU/lwith FT4 of 24.1 pmo/land TSH receptor antibody of 1.35 U/l. Hence she was started on propylthiouracil (PTU) during pregnancy. PTU was titrated down based on biochemical respons...

A 40-year-old female was referred for further management of thyrotoxicosis to GSTT. She worked as a nanny and had Graves’ thyrotoxicosis since October 2019. Her presenting symptoms were weight gain, hair loss, insomnia, and increasing anxiety. She had a large palpable goitre on examination with no eye disease. Ultrasound of the thyroid showed a diffusely enlarged thyroid with a normal echotexture, reflectivity and vascular flow. Benign subcentimeter nodules were seen in e...

A 75-year-old lady was referred to our centre from a local DGH, where she presented with constipation, reduced consciousness and acute confusion. She was found to have severe hypercalcaemia (Adjusted Calcium 5.21mmol/l), with PTH of 1473ng/l, and urine calcium of 13.8mg/24 h. Based on available biochemistry, a presumptive diagnosis of Parathyroid Carcinoma was made, and Hypercalcemia management was started. She was given about 3 litres of fluid and 60mg of pamidronate. Subsequ...